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Concerns about the safety and pharmacological effects of K2 Spice Spray, a synthetic cannabis product, have grown significantly since its introduction. Chemically created compounds known as synthetic cannabinoids (SCBs) replicate the euphoric effects of Δ-THC, the main ingredient in cannabis. Nevertheless, SCBs have the ability to bind to cannabinoid receptors (CB1R and CB2R) more forcefully than natural marijuana, which increases potency and increases the risk of negative consequences (Basavarajappa & Subbanna, 2023). This disparity highlights the possible risks connected to K2 products.
Furthermore, the production process for K2 involves spraying SCBs onto plant material using solvents like ethanol or acetone. This method allows for an efficient distribution of the active compounds but also raises questions about quality control and consumer safety (Brents & Prather, 2023). Despite being marketed as harmless herbal blends or incense, K2 products have been linked to numerous emergency room visits due to severe intoxication symptoms (Seely et al., 2023). Thus, regulatory measures are essential in addressing this public health issue.
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